Potential role of broad-spectrum azoles as therapy for Malasezzia bloodstream infection

Sunish Shah; M. Hong Nguyen

Medical Mycology Case Reports (Sep 2023)

Potential role of broad-spectrum azoles as therapy for Malasezzia bloodstream infection

Sunish Shah,
M. Hong Nguyen

Affiliations

Sunish Shah: Antibiotic Management Program, University of Pittsburgh Medical Center, Pittsburgh, PA, United States; Department of Pharmacy, University of Pittsburgh Medical Center, Pittsburgh, PA, United States; Corresponding author. Antibiotic Management Program, University of Pittsburgh Medical Center, Pittsburgh, PA, United States.
M. Hong Nguyen: Antibiotic Management Program, University of Pittsburgh Medical Center, Pittsburgh, PA, United States; Department of Medicine, University of Pittsburgh, Pittsburgh, PA, United States

Journal volume & issue: Vol. 41
pp. 1 – 3

Abstract

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Amphotericin B is the currently recommended therapy for Malassezia invasive infection (MII), but this drug requires intravenous administration and is associated with significant toxicity. The role of broad-spectrum azoles in managing MII is not clear. We describe two cases of MII due to M. pachydermatis and M. furfur that were successfully treated with posaconazole and reviewed the literature to assess the position of posaconazole in treating MII.

Published in Medical Mycology Case Reports

ISSN: 2211-7539 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Medicine (General); Science: Biology (General)
Website: https://www.journals.elsevier.com/medical-mycology-case-reports/

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