International Journal of Hyperthermia (Dec 2022)

Pleural decortication and hyperthermic intrathoracic chemotherapy for pseudomyxoma

  • Viktor Proesmans,
  • Tom Vandaele,
  • Jan Van Slambrouck,
  • Albert Wolthuis,
  • André D´Hoore,
  • Jeroen Dekervel,
  • Eric Van Cutsem,
  • Raphaëla Dresen,
  • Gert De Hertogh,
  • Karlien Degezelle,
  • Dirk Van Raemdonck,
  • Philippe Nafteux,
  • Laurens J. Ceulemans

DOI
https://doi.org/10.1080/02656736.2022.2104938
Journal volume & issue
Vol. 39, no. 1
pp. 1153 – 1157

Abstract

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Aim: Pleural dissemination of pseudomyxoma peritonei (PMP) is an extremely rare diagnosis, for which no standard therapy is available.Methods: We describe the successful treatment of a 67-year-old male diagnosed with left-sided intrapleural dissemination of PMP (low-grade appendiceal mucinous neoplasm), 2 years after treatment of abdominal PMP with cytoreductive surgery (CRS) and hyperthermic intra-peritoneal chemotherapy. Treatment consisted of extended pleural decortication (ePD) and oxaliplatin-based hyperthermic intrathoracic chemotherapy (HITHOC). The patient is doing well without complications or signs of recurrence, 26 months after thoracic surgery.Conclusion: ePD in combination with HITHOC is a valuable treatment for thoracic PMP.

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