Nature Communications (Feb 2022)
A role for ColV plasmids in the evolution of pathogenic Escherichia coli ST58
- Cameron J. Reid,
- Max L. Cummins,
- Stefan Börjesson,
- Michael S. M. Brouwer,
- Henrik Hasman,
- Anette M. Hammerum,
- Louise Roer,
- Stefanie Hess,
- Thomas Berendonk,
- Kristina Nešporová,
- Marisa Haenni,
- Jean-Yves Madec,
- Astrid Bethe,
- Geovana B. Michael,
- Anne-Kathrin Schink,
- Stefan Schwarz,
- Monika Dolejska,
- Steven P. Djordjevic
Affiliations
- Cameron J. Reid
- iThree Institute, University of Technology Sydney
- Max L. Cummins
- iThree Institute, University of Technology Sydney
- Stefan Börjesson
- Department of Animal Health and Antimicrobial Strategies, National Veterinary Institute (SVA)
- Michael S. M. Brouwer
- Wageningen Bioveterinary Research
- Henrik Hasman
- Department of Bacteria, Parasites and Fungi, Statens Serum Institut
- Anette M. Hammerum
- Department of Bacteria, Parasites and Fungi, Statens Serum Institut
- Louise Roer
- Department of Bacteria, Parasites and Fungi, Statens Serum Institut
- Stefanie Hess
- Institute of Microbiology, Technische Universität Dresden
- Thomas Berendonk
- Institute of Hydrobiology, Technische Universität Dresden
- Kristina Nešporová
- CEITEC VETUNI, University of Veterinary Sciences Brno
- Marisa Haenni
- Université de Lyon-ANSES, Unité Antibiorésistance et Virulence Bactériennes
- Jean-Yves Madec
- Université de Lyon-ANSES, Unité Antibiorésistance et Virulence Bactériennes
- Astrid Bethe
- Institute of Microbiology and Epizootics, Centre for Infection Medicine, Department of Veterinary Medicine, Freie Universität Berlin
- Geovana B. Michael
- Institute of Microbiology and Epizootics, Centre for Infection Medicine, Department of Veterinary Medicine, Freie Universität Berlin
- Anne-Kathrin Schink
- Institute of Microbiology and Epizootics, Centre for Infection Medicine, Department of Veterinary Medicine, Freie Universität Berlin
- Stefan Schwarz
- Institute of Microbiology and Epizootics, Centre for Infection Medicine, Department of Veterinary Medicine, Freie Universität Berlin
- Monika Dolejska
- CEITEC VETUNI, University of Veterinary Sciences Brno
- Steven P. Djordjevic
- iThree Institute, University of Technology Sydney
- DOI
- https://doi.org/10.1038/s41467-022-28342-4
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 15
Abstract
Escherichia coli ST58 has recently emerged as a globally disseminated extra-intestinal pathogen. Here, Reid et al. present a pan-genomic analysis of a global collection of ST58 isolates from animal and human sources, showing that ColV plasmid acquisition likely contributed to the divergence of a major sub-lineage that has a broad host range but is more commonly found in poultry and swine.
