Spectrum of endometrial pathology in patients with abnormal uterine bleeding: a rural population experience

Abstract

Introduction: Abnormal uterine bleeding (AUB) is one of the most common problems among women of all age groups. Endometrial sampling is a frequently performed procedure by the gynecologist that offers an opportunity to diagnose pathological conditions in the endometrium to accurately evaluate and diagnose the etiology. A study of the endometrium will establish the underlying cause and thereafter help the gynecologist to plan for the management. Aims: To study the histopathological pattern and spectrum of lesions in a patient with AUB. To analyze various pathological conditions and to highlight the importance of endometrial histology. Materials and Methods: This is a retrospective study that evaluated 83 patients with AUB by dilatation and curettage and/or endometrial biopsy of the rural population. Results: The most common endometrial pattern found to be hyperplasia without atypia (19/83) 22.9% followed by disordered proliferative (17/83) 19.27% and later by endometrial polyp (8/83) 9.63%, atypical hyperplasia/endometrioid intraepithelial neoplasia (1/83) 1.2% and lastly one case each of chronic non-specific endometritis, tuberculous endometritis, and histiocytic endometritis. There were 2/83 that is 2.4% case of endometrial adenocarcinoma with age range falling between above 50 years. Conclusion: Endometrial biopsy or curettage could be a safe and effective diagnostic step in the evaluation of AUB after ruling out medical causes with a detailed workup of the patient. This could help the clinician to design therapy for successful management.

Keywords

• abnormal uterine bleeding
• endometrial pattern
• endometrial polyp
• endometrium
• inadequate proliferative phase
• tuberculousendometritis