Journal of Clinical Medicine (Sep 2023)

Identification of Glaucoma in Diabetics Using the Laguna-ONhE Colourimetric Method and OCT Spectralis

  • Marta Gonzalez-Hernandez,
  • Nisamar Betancor-Caro,
  • Fatima Mesa-Lugo,
  • Ivan Rodriguez-Talavera,
  • Alicia Pareja-Rios,
  • Isabel Guedes-Guedes,
  • Beatriz Estevez-Jorge,
  • Maricela Trujillo-Blanco,
  • Roberto Cordova-Villegas,
  • Juan Espinoza-Gonzalez,
  • Leticia Siguero-Martin,
  • Carolina Goya-Gonzalez,
  • Maria Rodriguez-Dominguez,
  • Daniel Gonzalez-Hernandez,
  • Manuel Gonzalez de la Rosa

DOI
https://doi.org/10.3390/jcm12185876
Journal volume & issue
Vol. 12, no. 18
p. 5876

Abstract

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Background: Previous retrospective results are evaluated prospectively and blinded. Methods: A total of 221 eyes previously classified as normal (G1), 279 as moderate risk of glaucoma (G2) and 217 as high risk (G3) according to the Globin Discriminant Function (GDF) Laguna-ONhE index were examined with OCT Spectralis- Results: In G1, the Bruch’s Membrane Opening Minimum Rim Width (BMO-MRW) was 332 ± 55 microns; in G2, it was 252 ± 47 (p p p < 0.0001). Conclusions: In some cases, these defects appear to be mainly glaucomatous, and in others, they are associated with diabetic microangiopathy. In normal tension glaucoma, RNFL defects may be less severe than those inside the nerve.

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