PLoS ONE (Jan 2017)

Identifying artemisinin resistance from parasite clearance half-life data with a simple Shiny web application.

  • Sai Thein Than Tun,
  • Yoel Lubell,
  • Arjen M Dondorp,
  • Tom Fieldman,
  • Kyaw Myo Tun,
  • Olivier Celhay,
  • Xin Hui Chan,
  • Sompob Saralamba,
  • Lisa J White

DOI
https://doi.org/10.1371/journal.pone.0177840
Journal volume & issue
Vol. 12, no. 5
p. e0177840

Abstract

Read online

The emergence of artemisinin-resistant Plasmodium falciparum malaria is a major threat to malaria elimination. New tools for supporting the surveillance of artemisinin resistance are critical for current and future malaria control and elimination strategies. We have developed an open-access, user-friendly, web-based tool to analyse parasite clearance half-life data of P. falciparum infected patients after treatment with artemisinin derivatives, so that resistance to artemisinin can be identified. The tool can be accessed at bit.ly/id_artemisinin_resistance.