Data in Brief (Aug 2018)

Characterization data for T cell-specific Blimp-1 transgenic C57BL/6 mice

  • Aline Yen Ling Wang,
  • Charles Yuen Yung Loh,
  • Shyi-Jou Chen,
  • Huang-Kai Kao,
  • Cheng-Hung Lin,
  • Sheng-Hao Chuang,
  • Chin-Ming Lee,
  • Huey-Kang Sytwu,
  • Fu-Chan Wei

Journal volume & issue
Vol. 19
pp. 117 – 127

Abstract

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This article is the first to provide characterization data regarding naive C57BL/6 transgenic mice with overexpression of B lymphocyte-induced maturation protein 1 (Blimp-1) under a T cell-specific pLCK promoter. The data presented are related to phenotype, Blimp-1 overexpression levels, T cell development and T cell proliferation for Blimp-1 transgenic mice. For further Blimp-1 overexpressed T cell findings regarding skin allotransplantation, please refer to the research article “Blimp-1 prolongs allograft survival without regimen via influencing T cell development in favor of regulatory T cells while suppressing Th1” (Wang et al., 2018) [1]. Keywords: Blimp-1, Transgenic mice, T cell