npj Women's Health (Feb 2025)

Real world perspectives on endometriosis disease phenotyping through surgery, omics, health data, and artificial intelligence

  • Camran R. Nezhat,
  • Tomiko T. Oskotsky,
  • Joshua F. Robinson,
  • Susan J. Fisher,
  • Angie Tsuei,
  • Binya Liu,
  • Juan C. Irwin,
  • Brice Gaudilliere,
  • Marina Sirota,
  • David K. Stevenson,
  • Linda C. Giudice

DOI
https://doi.org/10.1038/s44294-024-00052-w
Journal volume & issue
Vol. 3, no. 1
pp. 1 – 16

Abstract

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Abstract Endometriosis is an enigmatic disease whose diagnosis and management are being transformed through innovative surgical, molecular, and computational technologies. Integrating single-cell and other omic disease data with clinical and surgical metadata can identify multiple disease subtypes with translation to novel diagnostics and therapeutics. Herein, we present real-world perspectives on endometriosis and the importance of multidisciplinary collaboration in informing molecular, epidemiologic, and cell-specific data in the clinical and surgical contexts.