Pulmonary Circulation (Sep 2019)

Acute response to rapid iloprost inhalation using the Breelib™ nebulizer in pulmonary arterial hypertension: the Breelib™ acute study

  • Manuel J. Richter,
  • Jun Wan,
  • Hossein A. Ghofrani,
  • Werner Seeger,
  • Henning Gall,
  • Andreas Rieth,
  • Khodr Tello

DOI
https://doi.org/10.1177/2045894019875342
Journal volume & issue
Vol. 9

Abstract

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The Breelib™ nebulizer was designed to reduce iloprost inhalation times for patients with pulmonary arterial hypertension (PAH). In 30 patients with PAH, rapid inhalation of iloprost 2.5 µg using Breelib™ caused significant improvements in invasively measured afterload and cardiac index but not echocardiographic right ventricular strain during 30 min post-inhalation.