Journal of Immunology Research (Jan 2023)

Understanding How Minerals Contribute to Optimal Immune Function

  • Alina Stefanache,
  • Ionut-Iulian Lungu,
  • Ioan-Adrian Butnariu,
  • Gabriela Calin,
  • Cristian Gutu,
  • Constantin Marcu,
  • Carmen Grierosu,
  • Elena Roxana Bogdan Goroftei,
  • Letitia-Doina Duceac,
  • Marius Gabriel Dabija,
  • Florina Popa,
  • Daniela Damir

DOI
https://doi.org/10.1155/2023/3355733
Journal volume & issue
Vol. 2023

Abstract

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Sufficient mineral supply is vital not only for the innate immune system but also for the components of the adaptive immune defense, which encompass defense mechanisms against pathogens and the delicate balance of pro- and anti-inflammatory regulation in the long term. Generally, a well-balanced diet is capable of providing the necessary minerals to support the immune system. Nevertheless, specific vulnerable populations should be cautious about obtaining adequate amounts of minerals such as magnesium, zinc, copper, iron, and selenium. Inadequate levels of these minerals can temporarily impair immune competence and disrupt the long-term regulation of systemic inflammation. Therefore, comprehending the mechanisms and sources of these minerals is crucial. In exceptional circumstances, mineral deficiencies may necessitate supplementation; however, excessive intake of supplements can have adverse effects on the immune system and should be avoided. Consequently, any supplementation should be approved by medical professionals and administered in recommended doses. This review emphasizes the crucial significance of minerals in promoting optimal functioning of the immune system. It investigates the indispensable minerals required for immune system function and the regulation of inflammation. Moreover, it delves into the significance of maintaining an optimized intake of minerals from a nutritional standpoint.