Rodent-Borne Orthohantaviruses in Vietnam, Madagascar and Japan

Fuka Kikuchi; Kae Senoo; Satoru Arai; Kimiyuki Tsuchiya; Nguyễn Trường Sơn; Masaharu Motokawa; Marie Claudine Ranorosoa; Saw Bawm; Kyaw San Lin; Hitoshi Suzuki; Akira Unno; Keisuke Nakata; Masashi Harada; Keiko Tanaka-Taya; Shigeru Morikawa; Motoi Suzuki; Tetsuya Mizutani; Richard Yanagihara

doi:10.3390/v13071343

Viruses (Jul 2021)

Rodent-Borne Orthohantaviruses in Vietnam, Madagascar and Japan

Fuka Kikuchi,
Kae Senoo,
Satoru Arai,
Kimiyuki Tsuchiya,
Nguyễn Trường Sơn,
Masaharu Motokawa,
Marie Claudine Ranorosoa,
Saw Bawm,
Kyaw San Lin,
Hitoshi Suzuki,
Akira Unno,
Keisuke Nakata,
Masashi Harada,
Keiko Tanaka-Taya,
Shigeru Morikawa,
Motoi Suzuki,
Tetsuya Mizutani,
Richard Yanagihara

Affiliations

Fuka Kikuchi: Center for Infectious Disease Epidemiology and Prevention Research, Tokyo University of Agriculture and Technology, Fuchu, Tokyo 183-8538, Japan
Kae Senoo: Center for Surveillance, Immunization, and Epidemiologic Research, National Institute of Infectious Diseases, Tokyo 162-8640, Japan
Satoru Arai: Center for Surveillance, Immunization, and Epidemiologic Research, National Institute of Infectious Diseases, Tokyo 162-8640, Japan
Kimiyuki Tsuchiya: Laboratory of Bioresources, Applied Biology Co., Ltd., Tokyo 107-0062, Japan
Nguyễn Trường Sơn: Institute of Ecology and Biological Resources, Vietnam Academy of Science and Technology, Hanoi 100000, Vietnam
Masaharu Motokawa: The Kyoto University Museum, Kyoto University, Kyoto 606-8501, Japan
Marie Claudine Ranorosoa: Mention Foresterie et Environnement, Ecole Supérieur des Sciences Agronomiques, Université d’Antananarivo, Antananarivo 101, Madagascar
Saw Bawm: Department of Pharmacology and Parasitology, University of Veterinary Science, Nay Pyi Taw 15013, Myanmar
Kyaw San Lin: Department of Aquaculture and Aquatic Disease, University of Veterinary Science, Nay Pyi Taw 15013, Myanmar
Hitoshi Suzuki: Laboratory of Ecology and Genetics, Graduate School of Environmental Science, Hokkaido University, Kita-ku, Sapporo 060-0810, Japan
Akira Unno: Local Independent Administrative Agency Hokkaido Research Organization, Bibai 079-0198, Japan
Keisuke Nakata: Local Independent Administrative Agency Hokkaido Research Organization, Bibai 079-0198, Japan
Masashi Harada: Laboratory Animal Center, Osaka City University, Sumiyoshi, Osaka 545-8585, Japan
Keiko Tanaka-Taya: Center for Surveillance, Immunization, and Epidemiologic Research, National Institute of Infectious Diseases, Tokyo 162-8640, Japan
Shigeru Morikawa: Department of Microbiology, Faculty of Veterinary Medicine, Okayama University of Science, Imabari 794-8555, Japan
Motoi Suzuki: Center for Surveillance, Immunization, and Epidemiologic Research, National Institute of Infectious Diseases, Tokyo 162-8640, Japan
Tetsuya Mizutani: Center for Infectious Disease Epidemiology and Prevention Research, Tokyo University of Agriculture and Technology, Fuchu, Tokyo 183-8538, Japan
Richard Yanagihara: Department of Pediatrics, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI 96813, USA

DOI: https://doi.org/10.3390/v13071343
Journal volume & issue: Vol. 13, no. 7
p. 1343

Abstract

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Hantaviruses are harbored by multiple small mammal species in Asia, Europe, Africa, and the Americas. To ascertain the geographic distribution and virus-host relationships of rodent-borne hantaviruses in Japan, Vietnam, Myanmar, and Madagascar, RNAlater™-preserved lung tissues of 981 rodents representing 40 species, collected in 2011–2017, were analyzed for hantavirus RNA by RT-PCR. Our data showed Hantaan orthohantavirus Da Bie Shan strain in the Chinese white-bellied rat (Niviventer confucianus) in Vietnam, Thailand; orthohantavirus Anjo strain in the black rat (Rattus rattus) in Madagascar; and Puumala orthohantavirus Hokkaido strain in the grey-sided vole (Myodes rufocanus) in Japan. The Hokkaido strain of Puumala virus was also detected in the large Japanese field mouse (Apodemus speciosus) and small Japanese field mouse (Apodemus argenteus), with evidence of host-switching as determined by co-phylogeny mapping.

Published in Viruses

ISSN: 1999-4915 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Microbiology
Website: http://www.mdpi.com/journal/viruses

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