BET inhibitors enhance the anti-cancer effect of etoposide by suppressing the MRN-ATM axis in the DNA damage response
Zhenhai Li,
Wenchao Xu,
Feng Chen,
Jun Zhang,
Wei-Guo Zhu
Affiliations
Zhenhai Li
Guangdong Key Laboratory of Genome Instability and Human Disease Prevention, Department of Biochemistry and Molecular Biology, Shenzhen University School of Medicine, Shenzhen, Guangdong 518055, China
Wenchao Xu
School of Pharmaceutical Sciences, Shenzhen University Health Science Center, Shenzhen, Guangdong 518055, China
Feng Chen
Guangdong Key Laboratory of Genome Instability and Human Disease Prevention, Department of Biochemistry and Molecular Biology, Shenzhen University School of Medicine, Shenzhen, Guangdong 518055, China
Jun Zhang
Guangdong Key Laboratory of Genome Instability and Human Disease Prevention, Department of Biochemistry and Molecular Biology, Shenzhen University School of Medicine, Shenzhen, Guangdong 518055, China; Corresponding author.
Wei-Guo Zhu
Guangdong Key Laboratory of Genome Instability and Human Disease Prevention, Department of Biochemistry and Molecular Biology, Shenzhen University School of Medicine, Shenzhen, Guangdong 518055, China; Base for International Science and Technology Cooperation: Carson Cancer Stem Cell Vaccines R&D Center, International Cancer Center, Shenzhen University Health Science Center, Shenzhen, Guangdong 518055, China; Shenzhen Bay Laboratory, Shenzhen University School of Medicine, Shenzhen, Guangdong 518055, China; Marshall Laboratory of Biomedical Engineering, Shenzhen University School of Medicine, Shenzhen, Guangdong 518055, China; Corresponding author. Department of Biochemistry and Molecular Biology, Shenzhen University School of Medicine, Shenzhen, Guangdong 518055, China.
