Data for the synthesis of new 4-aryloxy-N-arylanilines as potent succinate-cytochrome c reductase inhibitors
Hua Cheng,
Wei Song,
Ren Nie,
Yu-Xia Wang,
Hui-Lian Li,
Xiang-Sheng Jiang,
Jun-Jun Wu,
Cheng Chen,
Qiong-You Wu
Affiliations
Hua Cheng
Department of Chemical Engineering and Food Science, Hubei University of Arts and Science, Xiangyang 441053, PR China
Wei Song
Department of Chemical Engineering and Food Science, Hubei University of Arts and Science, Xiangyang 441053, PR China
Ren Nie
Department of Chemical Engineering and Food Science, Hubei University of Arts and Science, Xiangyang 441053, PR China
Yu-Xia Wang
Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, PR China
Hui-Lian Li
Department of Chemical Engineering and Food Science, Hubei University of Arts and Science, Xiangyang 441053, PR China
Xiang-Sheng Jiang
Department of Chemical Engineering and Food Science, Hubei University of Arts and Science, Xiangyang 441053, PR China
Jun-Jun Wu
Department of Chemical Engineering and Food Science, Hubei University of Arts and Science, Xiangyang 441053, PR China
Cheng Chen
State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan 430070, PR China; Corresponding authors.
Qiong-You Wu
Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, PR China; Corresponding authors.
In this data article, we have designed a simple and facile protocol for copper-mediated synthesis of new 4-aryloxy-N-arylanilines under mild reaction conditions. The general information and synthetic procedures of all the target compounds were provided, and they were fully characterized by Nuclear Magnetic Resonance (NMR, including 1H NMR and 13C NMR), melting point measurements, and High-Resolution Mass Spectroscopy (HRMS). Furthermore, the inhibitory activities of these compounds against succinate-cytochrome c reductase (SCR) were evaluated, and the methods and procedures of enzyme inhibition experiments were also recorded in this data article. This article is related to “Synthesis of new 4-aryloxy-N-arylanilines and their inhibitory activities against succinate-cytochrome c reductase” (Cheng et al., 2018) [1].