Nature Communications (Oct 2019)

A multiscale signalling network map of innate immune response in cancer reveals cell heterogeneity signatures

  • Maria Kondratova,
  • Urszula Czerwinska,
  • Nicolas Sompairac,
  • Sebastian D. Amigorena,
  • Vassili Soumelis,
  • Emmanuel Barillot,
  • Andrei Zinovyev,
  • Inna Kuperstein

DOI
https://doi.org/10.1038/s41467-019-12270-x
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 13

Abstract

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The complexity of the innate immune response to cancer makes interpretation of large data sets challenging. Here, the authors provide an integrated multi-scale map of signalling networks representing the different immune cells and their interactions and show its utility for data interpretation.