Communications Biology (Mar 2023)

CCR3 plays a role in murine age-related cognitive changes and T-cell infiltration into the brain

  • Sanket V. Rege,
  • Arnaud Teichert,
  • Juliet Masumi,
  • Onkar S. Dhande,
  • Reema Harish,
  • Brett W. Higgins,
  • Yesenia Lopez,
  • Lily Akrapongpisak,
  • Hannah Hackbart,
  • Sofia Caryotakis,
  • Dino P. Leone,
  • Balazs Szoke,
  • Jonas Hannestad,
  • Karoly Nikolich,
  • Steven P. Braithwaite,
  • S. Sakura Minami

DOI
https://doi.org/10.1038/s42003-023-04665-w
Journal volume & issue
Vol. 6, no. 1
pp. 1 – 11

Abstract

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CCR3 is shown to play a role in age-related T cell infiltration into the brain in mice as well as age-related changes in cognition, highlighting its therapeutic potential for age-related diseases.