Atrial Fibrillation and Heart Failure as the Onset of AL-Amyloidosis

Abstract

Left ventricular hypertrophy, atrial fibrillation and chronic heart failure are often in the practice of a cardiologist. The etiology of these conditions is very important because the correct early treatment. We are presenting a case of a late diagnosis of amyloidosis in a 53-year-old man. Despite the complex therapy, the course of the disease was complicated by the development of bilateral pneumonia, sepsis, disseminated intravascular coagulation and the patient died. Autopsy confirmed the diagnosis of systemic AL-amyloidosis (type Kappa) with massive damage to the heart, kidneys, lungs, liver, spleen, adrenal glands, thyroid gland, pancreas, gastrointestinal tract, subcutaneous fatty tissue and arterial vessels of the bone marrow. Thus, screening for amyloidosis is necessary in idiopathic LV thickening, atrial fibrillation, and heart failure for timely intravital diagnosis and therapy.

Keywords

• cardiac amyloidosis
• amyloid cardiomyopathy
• chronic heart failure with preserved ejection fraction
• atrial fibrillation
• left ventricular hypertrophy
• chronic kidney disease
• proteinuria
• nephrotic syndrome
• cardiorenal syndrome