Change in time of spectral characteristics of drug substances (nir region)

Abstract

The changes in NIR spectra of substances resulting from the processes of natural aging were investigated. The method of discriminant analysis was used for statistical evaluation of differences between two groups of spectra - for initial and aged substances. The values obtained for the spectral range of each substance can limit the possible dispersion of the samples arisen during their aging.

Keywords

• ближняя ИК-спектрометрия
• стабильность лекарственной субстанции
• срок годности
• спектральная библиотека