Renal Failure: The Most Important Prognostic Factor for Morbidity and Mortality in Patients Undergoing Open Elective Abdominal Aortic Aneurysm Repair

Abstract

Introduction: The elective abdominal aortic aneurysm repair leads to a remarkable decrease in the rupture of aneurysm and an increase in the life expectancy among patients. Aim: To study the mortality rate and complications of the open elective abdominal aortic aneurysm repair. Materials and Methods: This descriptive cross-sectional retrospective study was carried out on all patients who had undergone open elective abdominal aortic aneurysm repair in Rasht Hospitals, Iran, from March 2007 to March 2011. The background variables, i.e., preoperative, intraoperative, and postoperative results, as well as relevant variables including mortality and complications were recorded on a checklist. The data collected were analysed using SPSS 21.0 through univariate and multivariate analyses. Results: From the total of 61 patients, 11 (18%) were female and 50 (82%) of them were male. Nine patients (14.8%) died within 30 days from the surgery, and five patients (8.2%) suffered complications: Acute renal failure (three individuals) and sepsis (two individuals). In the univariate analysis, the Blood Urea Nitrogen (BUN) level of over 25 mg/dL (p=0.028) and the serum creatinine level of over 1.2 mg/dL (p=0.047) had a significant correlation with postoperative mortality. Additionally, the intensive care unit stay (p=0.019) and the duration of the mechanical ventilation (p=0.021) were significantly correlated with the postoperative complication occurrence. Conclusion: The BUN level of over 25 mg/dL and the serum creatinine level exceeding 1.2 mg/dL were the predictors of mortality, and the intensive care unit stay and the duration of the mechanical ventilation were the predictors of the postoperative complication occurrence after the open elective abdominal aortic aneurysm repair.

Keywords

• abdominal aortic aneurysm complications
• diagnosis
• risk factors