Diseases (Sep 2023)

Survival Analysis and Contributing Factors among PCR-Confirmed Adult Inpatients during the Endemic Phase of COVID-19

  • Verónica Benites-Godínez,
  • Oliver Mendoza-Cano,
  • Xóchitl Trujillo,
  • Mónica Ríos-Silva,
  • Agustin Lugo-Radillo,
  • Jaime Alberto Bricio-Barrios,
  • Herguin Benjamin Cuevas-Arellano,
  • Eder Fernando Ríos-Bracamontes,
  • Walter Serrano-Moreno,
  • Yolitzy Cárdenas,
  • Greta Mariana Baltazar-Rodríguez,
  • Ana Daniela Ortega-Ramírez,
  • Efrén Murillo-Zamora

DOI
https://doi.org/10.3390/diseases11030119
Journal volume & issue
Vol. 11, no. 3
p. 119

Abstract

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In May 2023, the global health emergency status of COVID-19 concluded, marking the onset of an endemic era. This study assessed survival rates among PCR-confirmed adult inpatients during this phase and determined contributing factors. Employing a survival analysis approach, this investigation utilized a nationwide Mexican cohort encompassing 152 adult inpatients. Survival rates were computed using the Kaplan–Meier method, and a proportional Cox model identified mortality risk factors. Survival rates remained above 65% on day 14 after admission. Vaccination status, including the number of doses administered, was not significantly associated with fatal outcomes. Chronic kidney disease or a history of immunosuppression (due to any cause) increased mortality risk. Our findings underscore the persistent severity of COVID-19 beyond the global health emergency, emphasizing the necessity for tailored interventions for vulnerable patients.

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