Frontiers in Cellular and Infection Microbiology (Jun 2020)

Cotton-Tipped Plastic Swabs for SARS-CoV-2 RT-qPCR Diagnosis to Prevent Supply Shortages

  • Byron Freire-Paspuel,
  • Patricio Vega-Mariño,
  • Alberto Velez,
  • Paulina Castillo,
  • Eliana Elizabeth Gomez-Santos,
  • Marilyn Cruz,
  • Miguel Angel Garcia-Bereguiain

DOI
https://doi.org/10.3389/fcimb.2020.00356
Journal volume & issue
Vol. 10

Abstract

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CDC and WHO guidelines for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) diagnosis only recommend synthetic fiber swabs for nasopharyngeal (NP) sampling. We show that cotton-tipped plastic swabs do not inhibit PCR and have equivalent performance to rayon swabs. Cotton-tipped plastic swabs are massively produced worldwide and would prevent swab supply shortages under the current high SARS-CoV-2 testing demands, particularly in developing countries.

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