Breast calcifications on mammography from systemic amyloidosis: A case report

Joanna Rossi, MD, MPH; Rebecca Wingfield, MD; Ashley Cimino-Mathews, MD

Radiology Case Reports (Sep 2024)

Breast calcifications on mammography from systemic amyloidosis: A case report

Joanna Rossi, MD, MPH,
Rebecca Wingfield, MD,
Ashley Cimino-Mathews, MD

Affiliations

Joanna Rossi, MD, MPH: Corresponding author.; Johns Hopkins University School of Medicine, 601 N. Caroline Street, Baltimore, MD 21287, USA
Rebecca Wingfield, MD: Johns Hopkins University School of Medicine, 601 N. Caroline Street, Baltimore, MD 21287, USA
Ashley Cimino-Mathews, MD: Johns Hopkins University School of Medicine, 601 N. Caroline Street, Baltimore, MD 21287, USA

Journal volume & issue: Vol. 19, no. 9
pp. 3740 – 3747

Abstract

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Calcifications on mammography from systemic disease at times meet diagnostic criteria for histologic sampling to exclude malignancy. We present a case of bilateral groups of new calcifications on mammography that yielded amyloidosis on core biopsy. Awareness of our patient's known diagnosis of systemic light chain amyloidosis (AL) prompted use of Congo red staining to confirm the histologic diagnosis. Knowledge of systemic diseases with possible manifestations on mammography can facilitate cogent and clinically relevant radiology-pathology correlation.

Published in Radiology Case Reports

ISSN: 1930-0433 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://www.sciencedirect.com/journal/radiology-case-reports

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Abstract

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