ULTRASTRUCTURAL PATHOLOGY OF THE LYMPHOID ORGANS IN JAPANESE QUAIL EMBRYOS IN EXPERIMENTAL OCHRATOXICOSIS

Abstract

Pare ochratoxin A (OA) was administered to 150 embryos through air sac route at the rate of 0.02 ~~/eg~~. In SO embryos, the diluent (propylene glycol) was administered at the same dose level through the same. route. Embryos were sacrificied on 13th and 16th day of incubation. UltrastructuraI observation in the bursa of Fabricius spleen and thymus. of OA inoculated embryos revealed time dependent changes, including changes in the shape of the nucleus with condensation of granular and fibrillar components of the nucleoli.