Mechanisms of inactivation of activated oxygen-containing metabolites by the antioxidant system of the respiratory tract

Abstract

The literature review presents the current data about various mechanisms of the respiratory antioxidant system to inactivate the oxygen-containing metabolites and the characteristics of oxidation-reduction reactions. The development of oxidative stress in the respiratory tract tissue, the distribution of generation fluxes of radical and non-radical activated oxygena-ted metabolites, the rate of inactivation of hydrogen peroxide by various mechanisms of the antioxidant system are discussed in detail. The value of the standard redox potential of biologically significant redox couples is presented. Molecular pathways of oxidative stress are described.

Keywords

• antioxidant system
• respiratory tract
• mechanisms of inactivation of activated oxygen-containing metabo- lites