47 Baseline blood DNA methylation-based immune profiles and tumor mutational burden predict survival outcomes in anti-PD-1 treated head and neck cancer patient

• Ze Zhang,
• Keisuke Shirai,
• Robert Haddad,
• Kartik Sehgal,
• Brock Christensen,
• Min Kyung Lee,
• Rondi Butler,
• John Wiencke,
• Devin Koestler,
• Geat Ramush,
• Annette Molinaro,
• Hannah Stolrow,
• Lucas A Salas,
• Karl Kelsey

Affiliations

Ze Zhang

1Dartmouth College, Lebanon, NH, USA

Keisuke Shirai

3Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA

Robert Haddad

2Dana-Farber Cancer Institute, Boston, MA, USA

Kartik Sehgal

2Dana-Farber Cancer Institute, Boston, MA, USA

Brock Christensen

1Dartmouth College, Lebanon, NH, USA

Min Kyung Lee

1Dartmouth College, Lebanon, NH, USA

Rondi Butler

4Brown University, Providence, RI, USA

John Wiencke

5University of California, San Francisco, San Francisco, CA, USA

Devin Koestler

6University of Kansas Medical Center, Kansas City, KS, USA

Geat Ramush

4Brown University, Providence, RI, USA

Annette Molinaro

5University of California, San Francisco, San Francisco, CA, USA

Hannah Stolrow

1Dartmouth College, Lebanon, NH, USA

Lucas A Salas

7Department of Epidemiology, Geisel School of Medicine at Dartmouth, Dartmouth Cancer Center, Lebanon, NH, USA

Karl Kelsey

4Brown University, Providence, RI, USA