Nature Communications (Jan 2022)

Cerebellar connectivity maps embody individual adaptive behavior in mice

  • Ludovic Spaeth,
  • Jyotika Bahuguna,
  • Theo Gagneux,
  • Kevin Dorgans,
  • Izumi Sugihara,
  • Bernard Poulain,
  • Demian Battaglia,
  • Philippe Isope

DOI
https://doi.org/10.1038/s41467-022-27984-8
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 19

Abstract

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The variability in synaptic connectivity observed at the cerebellar granule cell - Purkinje cell connection in mice accounts for motor behavior traits at the individual level, suggesting that cerebellar networks encode internal models underlying individual-specific motor adaptation.