Direct allylic C–H alkylation of enol silyl ethers enabled by photoredox–Brønsted base hybrid catalysis

Abstract

Allylic C–H activation of enol silyl ethers via one-electron oxidation is usually accompanied by undesired desilylation. Here, under hybrid photoredox and Brønsted base catalysis, the authors show the mild functionalization of enol silyl ethers, providing a platform to access an array of complex carbonyl compounds.