ESC Heart Failure (Oct 2021)

Combined evaluation of right ventricular function using echocardiography in non‐ischaemic dilated cardiomyopathy

  • Jumpei Ishiwata,
  • Masao Daimon,
  • Koki Nakanishi,
  • Tadafumi Sugimoto,
  • Takayuki Kawata,
  • Tomohiro Shinozaki,
  • Tomoko Nakao,
  • Megumi Hirokawa,
  • Naoko Sawada,
  • Yuriko Yoshida,
  • Eisuke Amiya,
  • Masaru Hatano,
  • Hiroyuki Morita,
  • Yutaka Yatomi,
  • Issei Komuro

DOI
https://doi.org/10.1002/ehf2.13519
Journal volume & issue
Vol. 8, no. 5
pp. 3947 – 3956

Abstract

Read online

Abstract Aims Although comprehensive assessment of right ventricular (RV) function using multiple echocardiographic parameters is recommended for management of patients with non‐ischaemic dilated cardiomyopathy (DCM), it is unclear which RV parameters to combine. Additionally, normalization of RV parameters by estimated pulmonary artery systolic pressure (PASP), in consideration of RV–pulmonary artery coupling, may be clinically significant. The aim of our study was to elucidate the best combination of echocardiographic RV functional parameters, with or without indexing for PASP, to predict outcome in patients with heart failure with reduced ejection fraction secondary to DCM. Methods and results We retrospectively analysed 109 DCM patients with left ventricular ejection fraction −8.6%) had significantly higher hazard ratio than those with either impairment alone (11.3 vs. 3.4, P < 0.001); the other combinations did not improve prognostic value. Conclusions Normalizing echocardiographic RV parameters for PASP did not improve the prognostic values for our population. Meanwhile, combined evaluation of FAC and RVLS improved risk stratification in patients with heart failure with reduced ejection fraction secondary to DCM.

Keywords