Frontiers in Immunology (Dec 2021)

Global Perspectives on Immunization Against SARS-CoV-2 During Pregnancy and Priorities for Future Research: An International Consensus Paper From the World Association of Infectious Diseases and Immunological Disorders

  • Bahaa Abu-Raya,
  • Shabir A. Madhi,
  • Shabir A. Madhi,
  • Saad B. Omer,
  • Saad B. Omer,
  • Gayatri Amirthalingam,
  • Michelle L. Giles,
  • Michelle L. Giles,
  • Katie L. Flanagan,
  • Katie L. Flanagan,
  • Katie L. Flanagan,
  • Katie L. Flanagan,
  • Petra Zimmermann,
  • Petra Zimmermann,
  • Miguel O’Ryan,
  • Marco A. Safadi,
  • Vassiliki Papaevangelou,
  • Kirsten Maertens,
  • Nasamon Wanlapakorn,
  • Vicens Diaz-Brito,
  • Eline Tommelein,
  • Susanna Esposito

DOI
https://doi.org/10.3389/fimmu.2021.808064
Journal volume & issue
Vol. 12

Abstract

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in pregnancy is associated with a higher risk for severe morbidity and mortality when compared with infection in non-pregnant women of childbearing age. An increasing number of countries recommend immunization against SARS-CoV-2 in pregnant women. Recent studies provide preliminary and supportive evidence on safety, immunogenicity and effectiveness of coronavirus disease 2019 (COVID-19) vaccines in pregnant women; however, important knowledge gaps remain which warrant further studies. This collaborative consensus paper provides a review of the current literature on COVID-19 vaccines in pregnant women, identifies knowledge gaps and outlines priorities for future research to optimize protection against SARS-CoV-2 in the pregnant women and their infants.

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