Nature Communications (Apr 2020)
Functional and molecular heterogeneity of D2R neurons along dorsal ventral axis in the striatum
- Emma Puighermanal,
- Laia Castell,
- Anna Esteve-Codina,
- Su Melser,
- Konstantin Kaganovsky,
- Charleine Zussy,
- Jihane Boubaker-Vitre,
- Marta Gut,
- Stephanie Rialle,
- Christoph Kellendonk,
- Elisenda Sanz,
- Albert Quintana,
- Giovanni Marsicano,
- Miquel Martin,
- Marcelo Rubinstein,
- Jean-Antoine Girault,
- Jun B. Ding,
- Emmanuel Valjent
Affiliations
- Emma Puighermanal
- IGF, CNRS, INSERM, Université Montpellier
- Laia Castell
- IGF, CNRS, INSERM, Université Montpellier
- Anna Esteve-Codina
- Centre for Genomic Regulation, Barcelona Institute of Science and Technology
- Su Melser
- INSERM U1215, Neurocentre Magendie
- Konstantin Kaganovsky
- Department of Neurosurgery and Department of Neurology and Neurological Sciences, Stanford University School of Medicine
- Charleine Zussy
- IGF, CNRS, INSERM, Université Montpellier
- Jihane Boubaker-Vitre
- IGF, CNRS, INSERM, Université Montpellier
- Marta Gut
- Centre for Genomic Regulation, Barcelona Institute of Science and Technology
- Stephanie Rialle
- IGF, CNRS, INSERM, Université Montpellier
- Christoph Kellendonk
- Departement of Psychology and Pharmacology, Columbia University
- Elisenda Sanz
- Neuroscience Institute, Department of Cell Biology, Physiology and Immunology, Autonomous University of Barcelona
- Albert Quintana
- Neuroscience Institute, Department of Cell Biology, Physiology and Immunology, Autonomous University of Barcelona
- Giovanni Marsicano
- INSERM U1215, Neurocentre Magendie
- Miquel Martin
- IGF, CNRS, INSERM, Université Montpellier
- Marcelo Rubinstein
- Instituto de Investigaciones en Ingeniería Genética y Biología Molecular, CONICET
- Jean-Antoine Girault
- INSERM UMR-S 1270
- Jun B. Ding
- Department of Neurosurgery and Department of Neurology and Neurological Sciences, Stanford University School of Medicine
- Emmanuel Valjent
- IGF, CNRS, INSERM, Université Montpellier
- DOI
- https://doi.org/10.1038/s41467-020-15716-9
- Journal volume & issue
-
Vol. 11,
no. 1
pp. 1 – 15
Abstract
Striatal dopaminoceptive neurons are molecularly and functionally heterogeneous. Here, the authors provide the translatome of D2R striatal neurons and identified hundreds of region specific molecular markers as well as testing their resource to shed light into function.
