Diurnal variation of HMG CoA reductase activity in rat intestine

S. Shefer; S. Hauser; V. Lapar; E.H. Mosbach

Journal of Lipid Research (Sep 1972)

Diurnal variation of HMG CoA reductase activity in rat intestine

S. Shefer,
S. Hauser,
V. Lapar,
E.H. Mosbach

Affiliations

S. Shefer: Department of Lipid Research of The Public Health Research Institute of the City of New York, Inc., and the Bureau of Laboratories, New York City Health Department, New York 10016
S. Hauser: Department of Lipid Research of The Public Health Research Institute of the City of New York, Inc., and the Bureau of Laboratories, New York City Health Department, New York 10016
V. Lapar: Department of Lipid Research of The Public Health Research Institute of the City of New York, Inc., and the Bureau of Laboratories, New York City Health Department, New York 10016
E.H. Mosbach: Department of Lipid Research of The Public Health Research Institute of the City of New York, Inc., and the Bureau of Laboratories, New York City Health Department, New York 10016

Journal volume & issue: Vol. 13, no. 5
pp. 571 – 573

Abstract

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HMG CoA reductase activity of rat intestinal mucosa has a diurnal rhythm which coincides with the diurnal variation of the hepatic HMG CoA reductase but has a lower amplitude. The rhythmic variation of the intestinal reductase was present in both jejunal and ileal crypt cell microsomes and was not abolished by cholestyramine administration.

Published in Journal of Lipid Research

ISSN: 0022-2275 (Print); 1539-7262 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Science: Chemistry: Organic chemistry: Biochemistry
Website: https://www.journals.elsevier.com/journal-of-lipid-research

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