Contemporary Clinical Trials Communications (Jun 2021)

Prolonged exposure therapy for PTSD among spinal cord injury survivors: Study protocol for a randomized controlled trial

  • Mark B. Powers,
  • Jamie R. Pogue,
  • Nicholas E. Curcio,
  • Sarita Patel,
  • Andrea Wierzchowski,
  • Estrella V. Thomas,
  • Ann Marie Warren,
  • Maris Adams,
  • Emma Turner,
  • Emily Carl,
  • Katherine Froehlich-Grobe,
  • Seema Sikka,
  • Michael Foreman,
  • Kiara Leonard,
  • Megan Douglas,
  • Monica Bennett,
  • Simon Driver

Journal volume & issue
Vol. 22
p. 100763

Abstract

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The National Spinal Cord Injury Statistical Center estimates 294,000 people in the US live with a spinal cord injury (SCI), with approximately 17,810 new cases each year. Although the physical outcomes associated with SCI have been widely studied, the psychological consequences of sustaining a SCI remain largely unexplored. Scant research has focused on posttraumatic stress disorder (PTSD) in this population, despite prevalence estimates suggesting that up to 60% of individuals with SCI experience PTSD post-injury, compared to only 7% of the general US population. Fortunately, prolonged exposure therapy (PE) is a well-researched and highly effective treatment for PTSD. However, no trauma focused exposure-based therapy for PTSD (e.g. PE) has not yet been tested in a SCI population. Thus, we aim to conduct the first test of an evidence-based intervention for PTSD among patients with SCI. Adults with SCI and PTSD (N = 60) will be randomly assigned to either: (1) 12-sessions of PE (2–3 sessions per week) or (2) a treatment as usual (TAU) control group who will receive the standard inpatient rehabilitation care for SCI patients. Primary outcomes will be assessed at 0, 6, 10, and 32 weeks.

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