Stabilization of MYC G-quadruplex DNA by ruthenium (II) complex overcomes imatinib resistance in chronic myeloid leukemia cells harboring T315I mutation

• Yuening Sun,
• Xin Chen,
• Siyan Liao,
• Aochu Liu,
• Huan Zhou,
• Liling Jiang,
• Wa Ding,
• Wenjie Mei,
• Jinbao Liu,
• Xianping Shi

Affiliations

Yuening Sun

Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation; State Key Laboratory of Respiratory Disease; Affiliated Cancer Hospital of Guangzhou Medical University School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, Guangdong 510120, China

Xin Chen

Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation; State Key Laboratory of Respiratory Disease; Affiliated Cancer Hospital of Guangzhou Medical University School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, Guangdong 510120, China

Siyan Liao

Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation; State Key Laboratory of Respiratory Disease; Affiliated Cancer Hospital of Guangzhou Medical University School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, Guangdong 510120, China

Aochu Liu

Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation; State Key Laboratory of Respiratory Disease; Affiliated Cancer Hospital of Guangzhou Medical University School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, Guangdong 510120, China

Huan Zhou

Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation; State Key Laboratory of Respiratory Disease; Affiliated Cancer Hospital of Guangzhou Medical University School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, Guangdong 510120, China

Liling Jiang

Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation; State Key Laboratory of Respiratory Disease; Affiliated Cancer Hospital of Guangzhou Medical University School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, Guangdong 510120, China

Wa Ding

Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation; State Key Laboratory of Respiratory Disease; Affiliated Cancer Hospital of Guangzhou Medical University School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, Guangdong 510120, China

Wenjie Mei

Guangdong Province Engineering Technology Center for Molecular Probe and Biomedicine Imaging, Guangdong Pharmaceutical University, Guangzhou, Guangdong 510006, China; Corresponding author.

Jinbao Liu

Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation; State Key Laboratory of Respiratory Disease; Affiliated Cancer Hospital of Guangzhou Medical University School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, Guangdong 510120, China; Corresponding author.

Xianping Shi

Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation; State Key Laboratory of Respiratory Disease; Affiliated Cancer Hospital of Guangzhou Medical University School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, Guangdong 510120, China; Corresponding author.