Diseases (Jun 2024)

Surgical Resection and Immediate Reconstruction with a Bilayer Wound Collagen Matrix of a Rare Oral Angiosarcoma: A Case Report

  • Enzo Iacomino,
  • Chiara Fratini,
  • Laura Sollima,
  • Alberto Eibenstein,
  • Christian Barbato,
  • Marco de Vincentiis,
  • Antonio Minni,
  • Federica Zoccali

DOI
https://doi.org/10.3390/diseases12060117
Journal volume & issue
Vol. 12, no. 6
p. 117

Abstract

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Angiosarcomas are malignant vascular tumors that commonly occur on the skin of the head and neck, breast, or scalp. Oral angiosarcoma is a rare tumor (0.0077% of all cancers in Europe), and regarding this atypical localization, no formal treatment trials have been conducted yet. We present a case of a 58-year-old female patient with a diagnosis of oral angiosarcoma. After tumor excision was performed by transoral surgical approach, immediate reconstruction of the intraoral surgical defects was made using Integra® bilayer wound collagen matrix. A skin regeneration technique has previously been reported to provide good healing for defects of buccal resection, preventing postoperative cicatricial fibrosis.

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