Nature Communications (Jan 2022)
Distinct kinetics of antibodies to 111 Plasmodium falciparum proteins identifies markers of recent malaria exposure
- Victor Yman,
- James Tuju,
- Michael T. White,
- Gathoni Kamuyu,
- Kennedy Mwai,
- Nelson Kibinge,
- Muhammad Asghar,
- Christopher Sundling,
- Klara Sondén,
- Linda Murungi,
- Daniel Kiboi,
- Rinter Kimathi,
- Timothy Chege,
- Emily Chepsat,
- Patience Kiyuka,
- Lydia Nyamako,
- Faith H. A. Osier,
- Anna Färnert
Affiliations
- Victor Yman
- Division of Infectious Diseases, Department of Medicine Solna and Center for Molecular Medicine, Karolinska Institutet
- James Tuju
- Kenya Medical Research Institute - Wellcome Trust Research Program, Centre for Geographical Medicine Research Coast
- Michael T. White
- Department of Parasites and Insect Vectors, Institut Pasteur
- Gathoni Kamuyu
- Kenya Medical Research Institute - Wellcome Trust Research Program, Centre for Geographical Medicine Research Coast
- Kennedy Mwai
- Kenya Medical Research Institute - Wellcome Trust Research Program, Centre for Geographical Medicine Research Coast
- Nelson Kibinge
- Kenya Medical Research Institute - Wellcome Trust Research Program, Centre for Geographical Medicine Research Coast
- Muhammad Asghar
- Division of Infectious Diseases, Department of Medicine Solna and Center for Molecular Medicine, Karolinska Institutet
- Christopher Sundling
- Division of Infectious Diseases, Department of Medicine Solna and Center for Molecular Medicine, Karolinska Institutet
- Klara Sondén
- Division of Infectious Diseases, Department of Medicine Solna and Center for Molecular Medicine, Karolinska Institutet
- Linda Murungi
- Kenya Medical Research Institute - Wellcome Trust Research Program, Centre for Geographical Medicine Research Coast
- Daniel Kiboi
- Kenya Medical Research Institute - Wellcome Trust Research Program, Centre for Geographical Medicine Research Coast
- Rinter Kimathi
- Kenya Medical Research Institute - Wellcome Trust Research Program, Centre for Geographical Medicine Research Coast
- Timothy Chege
- Kenya Medical Research Institute - Wellcome Trust Research Program, Centre for Geographical Medicine Research Coast
- Emily Chepsat
- Kenya Medical Research Institute - Wellcome Trust Research Program, Centre for Geographical Medicine Research Coast
- Patience Kiyuka
- Kenya Medical Research Institute - Wellcome Trust Research Program, Centre for Geographical Medicine Research Coast
- Lydia Nyamako
- Kenya Medical Research Institute - Wellcome Trust Research Program, Centre for Geographical Medicine Research Coast
- Faith H. A. Osier
- Kenya Medical Research Institute - Wellcome Trust Research Program, Centre for Geographical Medicine Research Coast
- Anna Färnert
- Division of Infectious Diseases, Department of Medicine Solna and Center for Molecular Medicine, Karolinska Institutet
- DOI
- https://doi.org/10.1038/s41467-021-27863-8
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 15
Abstract
Serological markers of recent Plasmodium falciparum infection could be useful to estimate incidence. Here, the authors identify a combination of five serological markers to detect exposure to infection within the previous three months with >80% sensitivity and specificity.
