Ethyl 2-hydroxy-2-phenyl-2-(thiazol-2-yl)acetate

Abstract

This short note describes the synthesis of the title compound through spontaneous aerobic oxidation of ethyl 2-phenyl-2-(thiazol-2-yl)acetate. Due to the prevalence of such functional motifs in biologically active substances, we believe the oxidation encountered highlights an important degradation pathway worthy of note.

Keywords

• thiazole
• oxidation product
• heterocycles