Molbank (May 2015)

Ethyl 2-hydroxy-2-phenyl-2-(thiazol-2-yl)acetate

  • Carl J. Mallia,
  • Lukas Englert,
  • Gary C. Walter,
  • Ian R. Baxendale

DOI
https://doi.org/10.3390/M857
Journal volume & issue
Vol. 2015, no. 2
p. M857

Abstract

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This short note describes the synthesis of the title compound through spontaneous aerobic oxidation of ethyl 2-phenyl-2-(thiazol-2-yl)acetate. Due to the prevalence of such functional motifs in biologically active substances, we believe the oxidation encountered highlights an important degradation pathway worthy of note.

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