Acta Médica del Centro (Apr 2017)

Characterization of neoplastic diseases in patients with functional renal transplantation

  • Osmany Antonio Hernández Pérez,
  • Lisbel Pérez Delgado,
  • Yuniesky Hernández González,
  • Elizabeth Díaz Mederos

Journal volume & issue
Vol. 11, no. 2
pp. 19 – 27

Abstract

Read online

Introduction: renal transplantation is the therapy of choice for the majority of patients with chronic renal failure. Immunosuppressive treatment shows associations with neoplastic diseases. Objective: to characterize neoplastic diseases in patients with functional renal transplantation. Method: an observational, descriptive, transverse study was carried out at "Arnaldo Milián Castro" Hospital. An intentional sample of 16 patients with neoplastic diseases was selected. Information was obtained from the renal transplant Consultation, from the clinical file and database of the Department of Pathological Anatomy. Results: male sex predominated (81%), mean age higher than female sex, and white skin color (93.7%). The most commonly used renal replacement therapy was hemodialysis (nine, 56%). Squamous cell carcinoma (six) and basal cell (three) prevailed. The frequency of viral diseases such as hepatitis C and cytomegalovirus was evidenced. Immunosuppressive treatment with prednisone, immuran, and cyclosporin was more than half of the patients (62%), and seven died after three years of neoplastic disease treatment for each patient. Conclusions: squamous cell carcinoma and basal cellular carcinoma were the most prevalent neoplastic diseases and after the treatment received, the survival was the expected.

Keywords