Communications Biology (Apr 2022)
Exome sequencing of families from Ghana reveals known and candidate hearing impairment genes
- Ambroise Wonkam,
- Samuel Mawuli Adadey,
- Isabelle Schrauwen,
- Elvis Twumasi Aboagye,
- Edmond Wonkam-Tingang,
- Kevin Esoh,
- Kalinka Popel,
- Noluthando Manyisa,
- Mario Jonas,
- Carmen deKock,
- Victoria Nembaware,
- Diana M. Cornejo Sanchez,
- Thashi Bharadwaj,
- Abdul Nasir,
- Jenna L. Everard,
- Magda K. Kadlubowska,
- Liz M. Nouel-Saied,
- Anushree Acharya,
- Osbourne Quaye,
- Geoffrey K. Amedofu,
- Gordon A. Awandare,
- Suzanne M. Leal
Affiliations
- Ambroise Wonkam
- Division of Human Genetics, Faculty of Health Sciences, University of Cape Town
- Samuel Mawuli Adadey
- Division of Human Genetics, Faculty of Health Sciences, University of Cape Town
- Isabelle Schrauwen
- Center for Statistical Genetics, Gertrude H. Sergievsky Center, and the Department of Neurology, Columbia University Medical Centre
- Elvis Twumasi Aboagye
- West African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana
- Edmond Wonkam-Tingang
- Division of Human Genetics, Faculty of Health Sciences, University of Cape Town
- Kevin Esoh
- Division of Human Genetics, Faculty of Health Sciences, University of Cape Town
- Kalinka Popel
- Division of Human Genetics, Faculty of Health Sciences, University of Cape Town
- Noluthando Manyisa
- Division of Human Genetics, Faculty of Health Sciences, University of Cape Town
- Mario Jonas
- Division of Human Genetics, Faculty of Health Sciences, University of Cape Town
- Carmen deKock
- Division of Human Genetics, Faculty of Health Sciences, University of Cape Town
- Victoria Nembaware
- Division of Human Genetics, Faculty of Health Sciences, University of Cape Town
- Diana M. Cornejo Sanchez
- Center for Statistical Genetics, Gertrude H. Sergievsky Center, and the Department of Neurology, Columbia University Medical Centre
- Thashi Bharadwaj
- Center for Statistical Genetics, Gertrude H. Sergievsky Center, and the Department of Neurology, Columbia University Medical Centre
- Abdul Nasir
- Department of Molecular Science and Technology, Ajou University
- Jenna L. Everard
- Center for Statistical Genetics, Gertrude H. Sergievsky Center, and the Department of Neurology, Columbia University Medical Centre
- Magda K. Kadlubowska
- Center for Statistical Genetics, Gertrude H. Sergievsky Center, and the Department of Neurology, Columbia University Medical Centre
- Liz M. Nouel-Saied
- Center for Statistical Genetics, Gertrude H. Sergievsky Center, and the Department of Neurology, Columbia University Medical Centre
- Anushree Acharya
- Center for Statistical Genetics, Gertrude H. Sergievsky Center, and the Department of Neurology, Columbia University Medical Centre
- Osbourne Quaye
- West African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana
- Geoffrey K. Amedofu
- Department of Eye, Ear, Nose, and Throat, School of Medical Sciences, Kwame Nkrumah University of Science and Technology
- Gordon A. Awandare
- West African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana
- Suzanne M. Leal
- Center for Statistical Genetics, Gertrude H. Sergievsky Center, and the Department of Neurology, Columbia University Medical Centre
- DOI
- https://doi.org/10.1038/s42003-022-03326-8
- Journal volume & issue
-
Vol. 5,
no. 1
pp. 1 – 16
Abstract
Whole-exome sequencing for 51 families in Ghana reveals 7 candidate genes associated with hearing impairment, 6 of which have previously been demonstrated to be expressed in the mouse inner ear.
