Tissue-resident macrophages are major tumor-associated macrophage resources, contributing to early TNBC development, recurrence, and metastases

Ryuichiro Hirano; Koki Okamoto; Miyu Shinke; Marika Sato; Shigeaki Watanabe; Hitomi Watanabe; Gen Kondoh; Tetsuya Kadonosono; Shinae Kizaka-Kondoh

doi:10.1038/s42003-023-04525-7

Communications Biology (Feb 2023)

Tissue-resident macrophages are major tumor-associated macrophage resources, contributing to early TNBC development, recurrence, and metastases

Ryuichiro Hirano,
Koki Okamoto,
Miyu Shinke,
Marika Sato,
Shigeaki Watanabe,
Hitomi Watanabe,
Gen Kondoh,
Tetsuya Kadonosono,
Shinae Kizaka-Kondoh

Affiliations

Ryuichiro Hirano: School of Life Science and Technology, Tokyo Institute of Technology
Koki Okamoto: School of Life Science and Technology, Tokyo Institute of Technology
Miyu Shinke: School of Life Science and Technology, Tokyo Institute of Technology
Marika Sato: School of Life Science and Technology, Tokyo Institute of Technology
Shigeaki Watanabe: School of Life Science and Technology, Tokyo Institute of Technology
Hitomi Watanabe: Institute for Life and Medical Sciences, Kyoto University, Sakyo
Gen Kondoh: Institute for Life and Medical Sciences, Kyoto University, Sakyo
Tetsuya Kadonosono: School of Life Science and Technology, Tokyo Institute of Technology
Shinae Kizaka-Kondoh: School of Life Science and Technology, Tokyo Institute of Technology

DOI: https://doi.org/10.1038/s42003-023-04525-7
Journal volume & issue: Vol. 6, no. 1
pp. 1 – 11

Abstract

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The role of mammary gland tissue-resident macrophages (MGTRMs) in the development of TNBC breast tumors and recurrence after surgery and chemotherapy is investigated.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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