Nature Communications (Feb 2018)
Closed-loop stimulation of temporal cortex rescues functional networks and improves memory
- Youssef Ezzyat,
- Paul A. Wanda,
- Deborah F. Levy,
- Allison Kadel,
- Ada Aka,
- Isaac Pedisich,
- Michael R. Sperling,
- Ashwini D. Sharan,
- Bradley C. Lega,
- Alexis Burks,
- Robert E. Gross,
- Cory S. Inman,
- Barbara C. Jobst,
- Mark A. Gorenstein,
- Kathryn A. Davis,
- Gregory A. Worrell,
- Michal T. Kucewicz,
- Joel M. Stein,
- Richard Gorniak,
- Sandhitsu R. Das,
- Daniel S. Rizzuto,
- Michael J. Kahana
Affiliations
- Youssef Ezzyat
- Department of Psychology, University of Pennsylvania
- Paul A. Wanda
- Department of Psychology, University of Pennsylvania
- Deborah F. Levy
- Department of Psychology, University of Pennsylvania
- Allison Kadel
- Department of Psychology, University of Pennsylvania
- Ada Aka
- Department of Psychology, University of Pennsylvania
- Isaac Pedisich
- Department of Psychology, University of Pennsylvania
- Michael R. Sperling
- Deparment of Neurology, Thomas Jefferson University Hospital
- Ashwini D. Sharan
- Department of Neurosurgery, Thomas Jefferson University Hospital
- Bradley C. Lega
- Department of Neurosurgery, University of Texas, Southwestern
- Alexis Burks
- Department of Neurosurgery, University of Texas, Southwestern
- Robert E. Gross
- Department of Neurosurgery, Emory University Hospital
- Cory S. Inman
- Department of Neurosurgery, Emory University Hospital
- Barbara C. Jobst
- Department of Neurology, Dartmouth-Hitchcock Medical Center
- Mark A. Gorenstein
- Department of Neurology, Dartmouth-Hitchcock Medical Center
- Kathryn A. Davis
- Department of Neurology, Hospital of the University of Pennsylvania
- Gregory A. Worrell
- Department of Neurology, Mayo Clinic
- Michal T. Kucewicz
- Department of Neurology, Mayo Clinic
- Joel M. Stein
- Department of Radiology, Hospital of the University of Pennsylvania
- Richard Gorniak
- Department of Radiology, Thomas Jefferson University Hospital
- Sandhitsu R. Das
- Department of Neurology, Hospital of the University of Pennsylvania
- Daniel S. Rizzuto
- Department of Psychology, University of Pennsylvania
- Michael J. Kahana
- Department of Psychology, University of Pennsylvania
- DOI
- https://doi.org/10.1038/s41467-017-02753-0
- Journal volume & issue
-
Vol. 9,
no. 1
pp. 1 – 8
Abstract
Memory lapses can occur due to ineffective encoding, but it is unclear if targeted brain stimulation can improve memory performance. Here, authors use a closed-loop system to decode and stimulate periods of ineffective encoding, showing that stimulation of lateral temporal cortex can enhance memory.
