Subtype and cell type specific expression of lncRNAs provide insight into breast cancer

Sunniva Stordal Bjørklund; Miriam Ragle Aure; Jari Häkkinen; Johan Vallon-Christersson; Surendra Kumar; Katrine Bull Evensen; Thomas Fleischer; Jörg Tost; OSBREAC; Kristine K. Sahlberg; Anthony Mathelier; Gyan Bhanot; Shridar Ganesan; Xavier Tekpli; Vessela N. Kristensen

doi:10.1038/s42003-022-03559-7

Communications Biology (Aug 2022)

Subtype and cell type specific expression of lncRNAs provide insight into breast cancer

Sunniva Stordal Bjørklund,
Miriam Ragle Aure,
Jari Häkkinen,
Johan Vallon-Christersson,
Surendra Kumar,
Katrine Bull Evensen,
Thomas Fleischer,
Jörg Tost,
OSBREAC,
Kristine K. Sahlberg,
Anthony Mathelier,
Gyan Bhanot,
Shridar Ganesan,
Xavier Tekpli,
Vessela N. Kristensen

Affiliations

Sunniva Stordal Bjørklund: Department of Medical Genetics, Oslo University Hospital
Miriam Ragle Aure: Department of Medical Genetics, Oslo University Hospital
Jari Häkkinen: Division of Oncology, Department of Clinical Sciences Lund, Lund University, Medicon Village
Johan Vallon-Christersson: Division of Oncology, Department of Clinical Sciences Lund, Lund University, Medicon Village
Surendra Kumar: Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet
Katrine Bull Evensen: Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet
Thomas Fleischer: Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet
Jörg Tost: Laboratory for Epigenetics and Environment, Centre National de Recherche en Génomique Humaine, CEA – Institut de Biologie Francois Jacob, University Paris Saclay
OSBREAC
Kristine K. Sahlberg: Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet
Anthony Mathelier: Department of Medical Genetics, Oslo University Hospital
Gyan Bhanot: Department of Physics and Astronomy, Rutgers University
Shridar Ganesan: Rutgers Cancer Institute of New Jersey
Xavier Tekpli: Department of Medical Genetics, Oslo University Hospital
Vessela N. Kristensen: Department of Medical Genetics, Oslo University Hospital

DOI: https://doi.org/10.1038/s42003-022-03559-7
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 14

Abstract

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Long non-coding RNAs (lncRNAs) have been shown to be involved in breast cancer pathogenesis through regulation of multiple steps of gene expression. lncRNA expression patterns are also associated with breast cancer clinicopathological features in large population-based cohorts.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

About the journal