Plant Biotechnology Persa (Jun 2022)
Medicinal Plants and Herbal Compounds: Cancer Prevention and Treatment
Abstract
The global burden of cancer is increasing due to aging, population growth, poor nutrition, inadequate exercise, as well as high-risk behaviors such as smoking and alcohol consumption. According to the World Health Organization, in 2008, the ASR (Age Standardized Rate) of cancers of both sexes (according to the global reference population) in Iran is 107.7 per 100,000 population, and its five most common cancers are stomach, breast, colorectum, Bladder, and leukemia. According to global ASR statistics, the most common cancers in both sexes are 181.6 and five cancers are lung, breast, colorectal, stomach, and prostate. With the increase in life expectancy and the increase in the aging index in the population of Iran, it is expected that the incidence of various cancers will increase in the coming years and a lot of humans and financial capitals will be wasted. On the other hand, with the advancement of technology in bioinformatics and molecular techniques, a lot of information has been obtained that will help in the early detection of cancer. Meanwhile, despite much research on cancer and its treatment, this disease is still one of the biggest health problems in human societies. This research has been prepared in the form of a library, also articles reported in authoritative sources such as Springer, Elsevier, PubMed, Nature, etc. in 2021. Alfalfa extract and Aloe vera L. have been used to treat breast cancer and prevent dermatitis. Nigella sativa and boron have been used in the treatment of prostate, breast, cervical and lung cancers. Wild pistachio has been shown to affect colon cancer cell line. Artichokes improve the liver, bile, lower cholesterol and blood lipids. The leaves of the Hedera plant (Hedera pasuchovii G.Woronow) have been shown to affect breast cancer cell line (MCF-7) and uterus (Hela) as well as blood lymphocytes. Bakhtiari savory has been effective on Hela cancer cell line. Considering that chemical drugs used in the treatment of cancer, in addition to creating drug resistance the study of medicinal plants and factors of natural origins, such as compounds derived from medicinal plants used in the treatment of cancer is one of the most important objectives of the present study.
