Бюллетень сибирской медицины (Oct 2017)

Clinical and metabolic effects of aminophosphonate therapy in children with heart rhythm disturbances

  • Olga V. Senatorova,
  • Elena B. Khramova,
  • Vadim A. Kuznetsov,
  • Oksana I. Sergeychik

DOI
https://doi.org/10.20538/1682-0363-2017-3-176-184
Journal volume & issue
Vol. 16, no. 3
pp. 176 – 184

Abstract

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The aim of the survey is to summarize and assess a number of studies that examined the clinical and metabolic effects of aminophosphonates, particularly dimephosphon, which possess antioxidant and membrane-stabilizing effects. This paper presents a differential effect of dimephosphon on cell membrane functional activity as well as on structural features of platelet membrane as a model of smooth muscle cell in combined therapy in children with different clinical varieties of sick sinus syndrome.

Keywords