Managament of Immunosuppression in Kidney Post Transplantation

Abstract

When histocompatibility differences exist between donor and recipient, it is necessary to modify or suppress the immune response in order to enable the recipient to accept a graft. Immunesuppressive therapy, in general, suppresses all immune responses, including those to bacteria, fungi and even malignant tumors. In the 1950s when clinical renal transplantation began, sublethal total body irradiation was employed. Currently immunosuppression is more safely induced pharmacologically. Agents used in humans to suppress the immune response are discussed in our paper.

Keywords

• immunosuppression medications
• protocols
• renal transplantation