Gastroenterology Research and Practice (Jan 2024)
C-Reactive Protein Is Not the Driver Factor in Ulcerative Colitis
Abstract
Conclusion: The results of our study suggest that CRP may not directly mediate ulcerative colitis. Instead, it is more likely to be a bystander that is present alongside with elevated inflammatory factors. Further investigation is warranted to determine the precise role of CRP in humans, given the significant limitations associated with the use of mouse models.