Gastroenterology Research and Practice (Jan 2024)

C-Reactive Protein Is Not the Driver Factor in Ulcerative Colitis

  • Zhong-Bo Ge,
  • Xin-Yun Zhang,
  • Chun-Miao Zhang,
  • Tao-Tao Xu,
  • Si-Yi Li,
  • Meng-Xiao Wei,
  • Xin-Yuan Ding,
  • Cai-Juan Bai,
  • Han Wang,
  • Hai-Hong Zhou,
  • Ming-Yu Wang

DOI
https://doi.org/10.1155/2024/1386147
Journal volume & issue
Vol. 2024

Abstract

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Conclusion: The results of our study suggest that CRP may not directly mediate ulcerative colitis. Instead, it is more likely to be a bystander that is present alongside with elevated inflammatory factors. Further investigation is warranted to determine the precise role of CRP in humans, given the significant limitations associated with the use of mouse models.