Radiology and Oncology (Aug 2021)

Morphological features of breast cancer circulating tumor cells in blood after physical and biological type of isolation

  • Jesenko Tanja,
  • Modic Ziva,
  • Kuhar Cvetka Grasic,
  • Cemazar Maja,
  • Matkovic Urska,
  • Miceska Simona,
  • Varl Jerneja,
  • Kuhar Anamarija,
  • Kloboves-Prevodnik Veronika

DOI
https://doi.org/10.2478/raon-2021-0033
Journal volume & issue
Vol. 55, no. 3
pp. 292 – 304

Abstract

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Circulating tumor cells (CTCs) have become an important biomarker in breast cancer. Different isolation tech-niques based on their biological or physical features were established. Currently, the most widely used methods for visualization after their separation are based on immunofluorescent staining, which does not provide the information on the morphology.

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