Clinical Interventions in Aging (Oct 2024)

Development and Preliminary Psychometric Testing of a Brief Tool to Measure Medication Adherence in Older Populations

  • Iovino P,
  • Obbia P,
  • De Luca V,
  • Donnoli C,
  • Patumi L,
  • Leonardini L,
  • Palummeri E,
  • Ruatta M,
  • Basso AM,
  • Longobucco Y,
  • Rasero L,
  • Liotta G,
  • Illario M

Journal volume & issue
Vol. Volume 19
pp. 1765 – 1772

Abstract

Read online

Paolo Iovino,1 Paola Obbia,2 Vincenzo De Luca,3 Clara Donnoli,4 Lola Patumi,5 Lisa Leonardini,5 Ernesto Palummeri,6 Manuela Ruatta,2 Anna Maddalena Basso,2 Yari Longobucco,1 Laura Rasero,1 Giuseppe Liotta,4 Maddalena Illario3 1Department of Health Sciences, University of Florence, Florence, Italy; 2Directorate of Health Professions, Local Health Agency Cuneo 1, Cuneo, Italy; 3Department of Public Health, Federico II University of Naples, Naples, Italy; 4Department of Biomedicine and Prevention, Tor Vergata University of Rome, Rome, Italy; 5Programma Mattone Internazionale Salute, ULSS 4 Veneto Orientale Local Health Agency, San Donà di Piave (VE), Italy; 6Ligurian Health Agency, Genoa, Liguria Region, ItalyCorrespondence: Maddalena Illario, Università degli Studi di Napoli Federico II, Via Sergio Pansini n.5, Napoli, 80131, Italy, Tel +39 081 7464211, Email [email protected]: Chronic diseases in older age are major sources of burden for healthcare systems. Compliance with medications is the key to treatment success for these patients, especially for frail individuals living in community settings. However, adherence to long-term medications in this population is not optimal, which leads to the need for frequent screening of compliance within large-scale public health surveys. In this context, a brief, simple and valid measure capturing medication adherence is not yet available. This study aims to develop and psychometrically test the Therapeutic Adherence Scale, a brief four-item tool that measures medication adherence in community-dwelling older adults affected by chronic diseases.Methods: We conducted a three-phase process of instrument development, content validity assessment and psychometric testing.Results: Of the candidate nine items derived from a review of the literature, only four were deemed essential to capture intentional and nonintentional nonadherence. These items underwent structural validity, convergent and known-groups validity, and internal consistency on a sample of 269 participants (mean age = 7.91 years, SD = 7.26). Confirmatory factor analysis confirmed satisfactory fit indices (RMSEA = 0.000, CFI = 1.00, TLI = 1.00). Scores of the TAS were higher for those perceiving loneliness (ρ = 0.33, p < 0.001), those declaring memory loss in the last year (ρ = 0.29, p < 0.001), and those exhibiting worse mental quality of life (ρ = − 0.15, p = 0.03) compared with the other groups. Cronbach’s alpha and split-half reliability coefficients were acceptable, with values of 0.68 and 0.77, respectively.Conclusion: The Therapeutic Adherence Scale is a brief, valid and reliable self-report measure of medication adherence that can be used in practice and research to screen patients living in community settings. This tool is also free to use, which contributes to advancing knowledge on the field of medication adherence of older adults affected by chronic diseases.Keywords: aged, factor analysis, medication adherence, patient-reported outcome, psychometrics, self-report, statistical, questionnaire

Keywords