Evaluation of Clinical Features of Patients Diagnosed with MIS-C

Abstract

Objective:Evaluation of clinical features and results in multisystem inflammatory syndrome in children (MIS-C) associated with coronavirus disease-2019.Method:Patients diagnosed with MIS-C between September 1, 2020 and February 25, 2021, followed at University of Health Sciences Turkey, İstanbul Bağcılar Training and Research Hospital, Clinic of Pediatrics were included. Their clinical findings and laboratory results were evaluated retrospectively.Results:The average age of 16 patients diagnosed with MIS-C was found to be 6.5 years; of them, 62.5% were male and 37.5% were female. Our patients had no chronic disease. Fever (100%) and stomachache (81.25%) were the most common symptoms. All patients had high levels of C-reactive protein, procalcitonin, D-dimer and pro-brain natriuretic peptide at the time of diagnosis. The average ejection fraction was found as 63.1% in echocardiography. Intravenous immunoglobulin, corticosteroids and acetylsalicylic acid were administered to all patients whereas enoxaparin and vasopressors were administered to 11 (68.75%) and 3 (18.5%) patients, respectively. Left ventricular ejection fraction was found to be within the normal range at all patients at the time of discharge. The average in patient follow-up was found to be 10 days.Conclusion:It is important to have a long-term follow-up of MIS-C patients, who show similar symptoms to Kawasaki disease and yet have their own particular symptoms and cardiac involvement, in order not to miss the opportunity of early diagnosis as well as cardiac complications.

Keywords

• covid-19
• mis-c
• pediatrics