Nature Communications (Aug 2022)

CK2-induced cooperation of HHEX with the YAP-TEAD4 complex promotes colorectal tumorigenesis

  • Yuegui Guo,
  • Zhehui Zhu,
  • Zhenyu Huang,
  • Long Cui,
  • Wei Yu,
  • Wanjin Hong,
  • Zhaocai Zhou,
  • Peng Du,
  • Chen-Ying Liu

DOI
https://doi.org/10.1038/s41467-022-32674-6
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 17

Abstract

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Hippo signalling is often deregulated in cancers. Here the authors show that CK2 enhances the cooperation of HHEX with YAP-TEAD complex to promote colorectal tumorigenesis.