SpyGlass-Guided Photodynamic Therapy for Unresectable Cholangiocarcinoma: A Case Report and Review of the Literature

Jiangjiao Zhou; Li Xiong; Wei Liu; Chun Liu; Chao He; Heng Zou; Yu Wen; Liangwu Lin

doi:10.3389/fonc.2022.890735

Frontiers in Oncology (Aug 2022)

SpyGlass-Guided Photodynamic Therapy for Unresectable Cholangiocarcinoma: A Case Report and Review of the Literature

Jiangjiao Zhou,
Li Xiong,
Wei Liu,
Chun Liu,
Chao He,
Heng Zou,
Yu Wen,
Liangwu Lin

Affiliations

Jiangjiao Zhou: Department of General Surgery, The Second Xiangya Hospital, Central South University, Changsha, China
Li Xiong: Department of General Surgery, The Second Xiangya Hospital, Central South University, Changsha, China
Wei Liu: Department of General Surgery, The Second Xiangya Hospital, Central South University, Changsha, China
Chun Liu: Department of General Surgery, The Second Xiangya Hospital, Central South University, Changsha, China
Chao He: Department of General Surgery, The Second Xiangya Hospital, Central South University, Changsha, China
Heng Zou: Department of General Surgery, The Second Xiangya Hospital, Central South University, Changsha, China
Yu Wen: Department of General Surgery, The Second Xiangya Hospital, Central South University, Changsha, China
Liangwu Lin: Powder Metallurgy Research Insititute, Central South University, Changsha, China

DOI: https://doi.org/10.3389/fonc.2022.890735
Journal volume & issue: Vol. 12

Abstract

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Endoscopic retrograde cholangiopancreatography (ERCP) and biliary stent placement are standard palliative care procedures for patients with unresectable cholangiocarcinoma. However, the bile duct mucosa cannot be observed directly during the placement of a light diffuser in photodynamic therapy (PDT) and biopsy. SpyGlass can solve the above two problems. In this paper, we report the case of a patient who presented with obstructive jaundice and underwent endobiliary stenting placement several times. However, cholangiocarcinoma hyperplasia still led to stent blockage. We applied SpyGlass to guide the accurate placement of a light diffuser and evaluated the tumor necrosis after PDT. Results revealed the good application effect of this device.

Published in Frontiers in Oncology

ISSN: 2234-943X (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Website: https://www.frontiersin.org/journals/oncology/

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