Nature Communications (Jan 2023)
HSFA1a modulates plant heat stress responses and alters the 3D chromatin organization of enhancer-promoter interactions
- Ying Huang,
- Jing An,
- Sanchari Sircar,
- Clara Bergis,
- Chloé Dias Lopes,
- Xiaoning He,
- Barbara Da Costa,
- Feng-Quan Tan,
- Jeremie Bazin,
- Javier Antunez-Sanchez,
- Maria Florencia Mammarella,
- Ravi-sureshbhai Devani,
- Rim Brik-Chaouche,
- Abdelhafid Bendahmane,
- Florian Frugier,
- Chongjing Xia,
- Christophe Rothan,
- Aline V. Probst,
- Zouine Mohamed,
- Catherine Bergounioux,
- Marianne Delarue,
- Yijing Zhang,
- Shaojian Zheng,
- Martin Crespi,
- Sotirios Fragkostefanakis,
- Magdy M. Mahfouz,
- Federico Ariel,
- Jose Gutierrez-Marcos,
- Cécile Raynaud,
- David Latrasse,
- Moussa Benhamed
Affiliations
- Ying Huang
- Université Paris-Saclay, CNRS, INRAE, Univ Evry, Institute of Plant Sciences Paris-Saclay (IPS2)
- Jing An
- Université Paris-Saclay, CNRS, INRAE, Univ Evry, Institute of Plant Sciences Paris-Saclay (IPS2)
- Sanchari Sircar
- Université Paris-Saclay, CNRS, INRAE, Univ Evry, Institute of Plant Sciences Paris-Saclay (IPS2)
- Clara Bergis
- Université Paris-Saclay, CNRS, INRAE, Univ Evry, Institute of Plant Sciences Paris-Saclay (IPS2)
- Chloé Dias Lopes
- Université Paris-Saclay, CNRS, INRAE, Univ Evry, Institute of Plant Sciences Paris-Saclay (IPS2)
- Xiaoning He
- Université Paris-Saclay, CNRS, INRAE, Univ Evry, Institute of Plant Sciences Paris-Saclay (IPS2)
- Barbara Da Costa
- Université Paris-Saclay, CNRS, INRAE, Univ Evry, Institute of Plant Sciences Paris-Saclay (IPS2)
- Feng-Quan Tan
- Université Paris-Saclay, CNRS, INRAE, Univ Evry, Institute of Plant Sciences Paris-Saclay (IPS2)
- Jeremie Bazin
- Université Paris-Saclay, CNRS, INRAE, Univ Evry, Institute of Plant Sciences Paris-Saclay (IPS2)
- Javier Antunez-Sanchez
- School of Life Science, University of Warwick
- Maria Florencia Mammarella
- Instituto de Agrobiotecnología del Litoral, CONICET, Universidad Nacional del Litoral
- Ravi-sureshbhai Devani
- Université Paris-Saclay, CNRS, INRAE, Univ Evry, Institute of Plant Sciences Paris-Saclay (IPS2)
- Rim Brik-Chaouche
- Université Paris-Saclay, CNRS, INRAE, Univ Evry, Institute of Plant Sciences Paris-Saclay (IPS2)
- Abdelhafid Bendahmane
- Université Paris-Saclay, CNRS, INRAE, Univ Evry, Institute of Plant Sciences Paris-Saclay (IPS2)
- Florian Frugier
- Université Paris-Saclay, CNRS, INRAE, Univ Evry, Institute of Plant Sciences Paris-Saclay (IPS2)
- Chongjing Xia
- Wheat Research Institute, School of Life Sciences and Engineering, Southwest University of Science and Technology
- Christophe Rothan
- INRA and University of Bordeaux, UMR 1332 Biologie du Fruit et Pathologie
- Aline V. Probst
- GReD, Université Clermont Auvergne, CNRS, INSERM, BP 38
- Zouine Mohamed
- Laboratoire Génomique et Biotechnologie du Fruit (GBF), UMR990, INRA/INP-ENSAT
- Catherine Bergounioux
- Université Paris-Saclay, CNRS, INRAE, Univ Evry, Institute of Plant Sciences Paris-Saclay (IPS2)
- Marianne Delarue
- Université Paris-Saclay, CNRS, INRAE, Univ Evry, Institute of Plant Sciences Paris-Saclay (IPS2)
- Yijing Zhang
- State Key Laboratory of Genetic Engineering, Collaborative Innovation Center of Genetics and Development, Department of Biochemistry, Institute of Plant Biology, School of Life Sciences, Fudan University
- Shaojian Zheng
- State Key Laboratory of Plant Physiology and Biochemistry, College of Life Sciences, Zhejiang University
- Martin Crespi
- Université Paris-Saclay, CNRS, INRAE, Univ Evry, Institute of Plant Sciences Paris-Saclay (IPS2)
- Sotirios Fragkostefanakis
- Department of Biosciences, Molecular Cell Biology of Plants, Goethe University Frankfurt am Main
- Magdy M. Mahfouz
- Division of Biological and Environmental Sciences and Engineering, King Abdullah University of Science and Technology
- Federico Ariel
- Instituto de Agrobiotecnología del Litoral, CONICET, Universidad Nacional del Litoral
- Jose Gutierrez-Marcos
- School of Life Science, University of Warwick
- Cécile Raynaud
- Université Paris-Saclay, CNRS, INRAE, Univ Evry, Institute of Plant Sciences Paris-Saclay (IPS2)
- David Latrasse
- Université Paris-Saclay, CNRS, INRAE, Univ Evry, Institute of Plant Sciences Paris-Saclay (IPS2)
- Moussa Benhamed
- Université Paris-Saclay, CNRS, INRAE, Univ Evry, Institute of Plant Sciences Paris-Saclay (IPS2)
- DOI
- https://doi.org/10.1038/s41467-023-36227-3
- Journal volume & issue
-
Vol. 14,
no. 1
pp. 1 – 15
Abstract
Here the authors show genome-wide chromatin changes and transcriptional reprogramming occur in response to heat stress in tomato, leading to the transient formation of promoter-enhancer contacts to drive the expression of heat-stress responsive genes. Furthermore, they show chromatin spatial reorganization requires HSFA1a, a transcription factor (TF) essential for heat stress tolerance in tomato.
